Description

3-(4-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester is a high-purity fluorinated organic building block essential for advanced chemical synthesis. This compound is valued for its trifluoromethylphenyl group, which imparts unique electronic and lipophilic properties to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates. The CAS number for this substance is 82989-27-3.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving their performance and durability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and reductions to introduce the 4-(trifluoromethyl)benzyl moiety into complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial labs for method development and exploring structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	3-(4-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	82989-27-3
Molecular Formula	C₁₂H₁₃F₃O₂
Molecular Weight	246.23 g/mol
Synonyms	Ethyl 3-[4-(Trifluoromethyl)phenyl]propanoate; 3-[4-(Trifluoromethyl)phenyl]propionic Acid Ethyl Ester; Ethyl 4-(Trifluoromethyl)hydrocinnamate; Ethyl 3-(p-Trifluoromethylphenyl)propionate; 82989-27-3; p-Trifluoromethylphenylpropionic Acid Ethyl Ester; 3-(4-Trifluoromethylphenyl)propanoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 3-(4-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.