Description

Methyl (2-Methyl-3-Trimethylsiloxycyclopropane-Carboxylate) is a specialized organosilicon compound featuring a cyclopropane ring, a carboxylate ester, and a trimethylsiloxy protecting group. This unique structure makes it a valuable protected intermediate and building block in advanced organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical sectors for the construction of complex molecules, where its functional groups allow for selective transformations under controlled conditions.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing cyclopropane motifs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the cyclopropane ring is a common bioactive structural element.
• Advanced Material Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and silicon-containing advanced materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for cyclopropanation reactions, ester transformations, and as a source of the trimethylsiloxy group.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of fine chemicals, offering a handle for selective deprotection and further functionalization.

Basic Information

Product Name	Methyl (2-Methyl-3-Trimethylsiloxycyclopropane-Carboxylate)
CAS No.	82884-40-0
Molecular Formula	C10H20O3Si
Molecular Weight	216.35 g/mol
Synonyms	Methyl 2-methyl-3-[(trimethylsilyl)oxy]cyclopropanecarboxylate; 2-Methyl-3-(trimethylsiloxy)cyclopropanecarboxylic acid methyl ester; Cyclopropanecarboxylic acid, 2-methyl-3-[(trimethylsilyl)oxy]-, methyl ester; Methyl 2-methyl-3-(trimethylsilyloxy)cyclopropanecarboxylate; (2-Methyl-3-trimethylsiloxycyclopropyl)carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl (2-Methyl-3-Trimethylsiloxycyclopropane-Carboxylate) adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for synthetic applications. Every lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.