Description

3-Bromo-4-Fluoro-Benzoic Acid Methyl Ester is a high-purity fluorinated and brominated aromatic ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and constructing functionalized aromatic systems.
• Fluorine Chemistry Studies: Used as a model compound in studying the effects of fluorine and bromine atoms on aromatic reactivity and physical properties.

Basic Information

Product Name	3-Bromo-4-Fluoro-Benzoic Acid Methyl Ester
CAS No.	82702-31-6
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	Methyl 3-Bromo-4-fluorobenzoate; 3-Bromo-4-fluorobenzoic Acid Methyl Ester; 4-Fluoro-3-bromobenzoic Acid Methyl Ester; Benzoic acid, 3-bromo-4-fluoro-, methyl ester; Methyl 4-fluoro-3-bromobenzoate; 82702-31-6; Methyl 3-bromo-4-fluorobenzoate
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluoro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring consistency, traceability, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.