Description

2-Chloro-5-(Chloromethyl)Pyridine Hydrochloride is a high-purity, versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its dual reactive sites, enabling the construction of complex molecular architectures essential for modern chemical development. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of functional polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-5-(Chloromethyl)Pyridine Hydrochloride
CAS No.	82674-16-6
Molecular Formula	C6H6Cl2N • HCl
Molecular Weight	198.48 g/mol (Free base: 162.02 g/mol)
Synonyms	5-(Chloromethyl)-2-chloropyridine hydrochloride; 2-Chloro-5-(chloromethyl)pyridine HCl; 2-Chloro-5-chloromethylpyridine hydrochloride; Pyridine, 2-chloro-5-(chloromethyl)-, hydrochloride; 82674-16-6; (2-Chloro-5-pyridinyl)methyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(Chloromethyl)Pyridine Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.