Description

2,6-Dichloro-5-Fluoro-3-Pyridinecarbonitrile is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, where the chlorine and fluorine substituents offer distinct sites for selective functionalization, enabling the construction of complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly in the synthesis of fluorinated pyridine derivatives.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in creating fluorinated drug candidates with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides, insecticides, and fungicides, leveraging the pyridine core for biological activity.
• Material Science Research: Used in the synthesis of specialized ligands, functionalized polymers, and organic electronic materials due to its robust heterocyclic structure.
• Chemical Development: Employed in process chemistry for route scouting and scale-up of complex molecules requiring a halogenated pyridine scaffold.
• Fluorine Chemistry: Acts as a valuable substrate for studying nucleophilic aromatic substitution (SNAr) reactions and other transformations involving fluorine and chlorine atoms.

Basic Information

Product Name	2,6-Dichloro-5-Fluoro-3-Pyridinecarbonitrile
CAS No.	82671-02-1
Molecular Formula	C6HCl2FN2
Molecular Weight	190.99 g/mol
Synonyms	5-Fluoro-2,6-dichloronicotinonitrile; 2,6-Dichloro-5-fluoronicotinonitrile; 3-Cyano-2,6-dichloro-5-fluoropyridine; 5-Fluoro-2,6-dichloro-3-pyridinecarbonitrile; 82671-02-1; 2,6-Dichloro-5-fluoro-3-cyanopyridine; 5-Fluoro-2,6-dichloro-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-5-Fluoro-3-Pyridinecarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.