Description

3-Nitro-2-Pyridyl Disulfide is a specialized heterocyclic organic compound featuring a nitro-substituted pyridine ring linked by a disulfide bridge. This unique structure makes it a valuable reagent for bioconjugation and protein chemistry, particularly for the reversible modification of thiol groups. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for applications such as peptide synthesis, cross-linking, and the development of diagnostic assays.

Application

• Bioconjugation Reagent: Used for the site-specific modification of cysteine residues in proteins and peptides.
• Cross-linking Agent: Facilitates the formation of reversible disulfide bonds between biomolecules for structural studies.
• Protecting Group Chemistry: Serves as a protecting group for thiols in multi-step organic synthesis.
• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Chemical Biology Probes: Employed in the development of activity-based probes for studying enzyme function.
• Diagnostic Assay Development: Used in the preparation of labeled antibodies and antigens for immunoassays.

Basic Information

Product Name	3-Nitro-2-Pyridyl Disulfide
CAS No.	82650-28-0
Molecular Formula	C10H6N4O4S2
Molecular Weight	310.31 g/mol
Synonyms	2,2'-Dithiobis(3-nitropyridine); 3-Nitro-2-pyridyl disulfide; Bis(3-nitro-2-pyridyl) disulfide; 3-Nitro-2-pyridyl disulphide; 3-Nitro-2-pyridyl disulfane; 3-Nitropyridine-2-thiol disulfide; 3-Nitro-2-pyridyl disulfide (NPDS); 3-Nitro-2-pyridyl disulfide reagent
EINECS	Contact for details

Quality Control

Our 3-Nitro-2-Pyridyl Disulfide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch to meet the stringent requirements of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.