Description

4-Nitrophlorizin is a chemically modified derivative of phlorizin, a natural dihydrochalcone glucoside. This nitrated analog is a valuable intermediate and research chemical for advanced biochemical and pharmacological studies. It is primarily utilized by pharmaceutical R&D laboratories and academic institutions investigating enzyme inhibition, metabolic pathways, and novel therapeutic agents.

Application

• Pharmaceutical Research: Serves as a key synthetic intermediate in the development of new drug candidates and bioactive molecules.
• Biochemical Studies: Used as a tool compound for investigating sodium-glucose linked transporter (SGLT) interactions and related metabolic enzymes.
• Reference Standard: Employed as an analytical standard in HPLC and LC-MS methods for quality control and method validation in research settings.
• Academic Research: Utilized in university and institutional labs for studies in medicinal chemistry, natural product derivatization, and structure-activity relationship (SAR) analysis.
• Chemical Synthesis: Acts as a specialized building block for the synthesis of more complex fluorinated or nitrated chalcone derivatives.

Basic Information

Product Name	4-Nitrophlorizin
CAS No.	82628-84-0
Molecular Formula	C21H23NO11
Molecular Weight	465.41 g/mol
Synonyms	4'-Nitrophlorizin; Phlorizin 4'-nitrate; 1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxy-3-nitrophenyl)-1-propanone; 4-Nitro-2',4',6'-trihydroxydihydrochalcone 4'-O-β-D-glucopyranoside; 4-Nitro-phloridzin
EINECS	Contact for details

Quality Control

Our 4-Nitrophlorizin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC purity and spectroscopic identification (NMR, IR, MS). A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.