Description

D-Lysine, N2-[(1,1-Dimethylethoxy)Carbonyl]-N6-[(Phenylmethoxy)Carbonyl]-, Methyl Ester is a protected derivative of the essential amino acid L-lysine, featuring orthogonal Boc and Cbz protecting groups on its side chain amines. This compound is a critical building block in solid-phase and solution-phase peptide synthesis, enabling the precise construction of complex peptides and proteins. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Peptide Synthesis Intermediate: A key protected amino acid monomer for the automated synthesis of custom peptides.
• Pharmaceutical Research: Used in the R&D of peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or drug delivery systems.
• Chemical Biology Probes: Incorporation into activity-based probes or affinity tags for studying protein function and interactions.
• Academic Research: Fundamental studies in organic chemistry, biochemistry, and medicinal chemistry exploring structure-activity relationships.
• Reference Standard: Used as a high-purity analytical standard for quality control in peptide manufacturing.

Basic Information

Product Name	D-Lysine, N2-[(1,1-Dimethylethoxy)Carbonyl]-N6-[(Phenylmethoxy)Carbonyl]-, Methyl Ester
CAS No.	82611-49-2
Molecular Formula	C20H30N2O6
Molecular Weight	394.47 g/mol
Synonyms	Boc-Lys(Cbz)-OMe; Nα-Boc-Nε-Cbz-D-lysine methyl ester; (2R)-6-{[(Benzyloxy)carbonyl]amino}-2-{[(tert-butoxy)carbonyl]amino}hexanoic acid methyl ester; Methyl N2-(tert-butoxycarbonyl)-N6-(benzyloxycarbonyl)-D-lysinate; Boc-D-Lys(Cbz)-OCH3; D-Lysine, N2-(tert-butoxycarbonyl)-N6-(benzyloxycarbonyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Boc/Cbz-protected D-Lysine methyl ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity, suitable for demanding synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere (nitrogen or argon) after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.