Description

Ethyl-(5S)-Benzoyloxy 6-Oxohexenoate is a high-purity chiral intermediate with significant synthetic utility. Its defined stereochemistry and functional groups make it a valuable building block for the production of complex, biologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for advanced synthesis projects.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for prostaglandin analogs and other bioactive compounds.
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to construct molecules with specific three-dimensional configurations critical for drug efficacy.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: Employed in method development and exploratory chemistry for creating novel molecular libraries and investigating new synthetic pathways.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	Ethyl-(5S)-Benzoyloxy 6-Oxohexenoate
CAS No.	82493-58-1
Molecular Formula	C15H16O5
Molecular Weight	276.29 g/mol
Synonyms	Ethyl (5S)-6-Oxo-5-(benzoyloxy)hex-2-enoate; (5S)-5-Benzoyloxy-6-oxo-hex-2-enoic Acid Ethyl Ester; Ethyl (5S)-5-(Benzoyloxy)-6-oxohex-2-enoate; 6-Oxo-5-(benzoyloxy)-2-hexenoic Acid Ethyl Ester, (5S)-; (S)-Ethyl 5-(benzoyloxy)-6-oxohex-2-enoate; Prostaglandin Intermediate
EINECS	Contact for details

Quality Control

Our Ethyl-(5S)-Benzoyloxy 6-Oxohexenoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is sensitive to strong bases and should be kept away from incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.