Description

5-Ethynyl-2-Pyridinamine is a versatile pyridine derivative featuring an ethynyl substituent, serving as a key building block in advanced organic synthesis. Its primary value lies in its dual functional groups, which allow for selective modifications via click chemistry and cross-coupling reactions, making it indispensable for constructing complex molecular architectures. This high-purity intermediate is critically needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers, conductive materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed as a tagging reagent or probe in bio-conjugation and activity-based protein profiling due to its reactive alkyne handle.
• Ligand Synthesis: Acts as a starting material for preparing sophisticated ligands used in catalysis and coordination chemistry.
• Academic & Contract Research: Essential for fundamental organic chemistry research and discovery projects in CROs and university laboratories.

Basic Information

Product Name	5-Ethynyl-2-Pyridinamine
CAS No.	82454-61-3
Molecular Formula	C7H6N2
Molecular Weight	118.14 g/mol
Synonyms	5-Ethynylpyridin-2-amine; 2-Amino-5-ethynylpyridine; 5-Ethynyl-2-aminopyridine; 5-Ethynyl-2-pyridylamine; 2-Pyridinamine, 5-ethynyl-; 5-Ethynyl-2-pyridineamine
EINECS	Contact for details

Quality Control

Our 5-Ethynyl-2-Pyridinamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.