Description

2-Propen-1-One, 3-Phenyl-1-(2,4,6-Trihydroxyphenyl)-, (E)- is a specialized organic compound belonging to the class of chalcone derivatives. This chemical matters as a versatile synthetic intermediate and a compound of significant interest in pharmaceutical and materials research due to its unique conjugated structure. It is needed by research and development laboratories, fine chemical manufacturers, and industries focused on developing novel active pharmaceutical ingredients (APIs), organic light-emitting diodes (OLEDs), and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and metabolic disorders.
• Organic Electronic Materials: Used in research for developing charge-transport materials, emitters, or sensitizers in OLEDs and organic photovoltaic (OPV) cells.
• Chemical Biology & Biochemistry: Acts as a probe or inhibitor in studying biological pathways and enzyme functions due to its specific molecular interactions.
• Advanced Organic Synthesis: Employed as a precursor for synthesizing more complex heterocyclic compounds, flavonoids, and natural product analogs.
• Material Science Research: Investigated for its potential in creating novel polymers, coatings, or supramolecular assemblies with specific optical properties.
• Analytical Reference Standard: Supplied as a high-purity compound for use as a standard in chromatographic analysis and method development.

Basic Information

Item	Detail
Product Name	2-Propen-1-One, 3-Phenyl-1-(2,4,6-Trihydroxyphenyl)-, (E)-
CAS No.	82451-30-7
Molecular Formula	C15H12O4
Molecular Weight	256.25 g/mol
Synonyms	(E)-3-Phenyl-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one; 2',4',6'-Trihydroxychalcone; 1-(2,4,6-Trihydroxyphenyl)-3-phenyl-2-propen-1-one; Phloretin Chalcone; NSC 407296; 2-Propen-1-one, 3-phenyl-1-(2,4,6-trihydroxyphenyl)-, (E)-; (E)-1-(2,4,6-Trihydroxyphenyl)-3-phenylprop-2-en-1-one
EINECS	Contact for details

Quality Control

Our 2-Propen-1-One, 3-Phenyl-1-(2,4,6-Trihydroxyphenyl)-, (E)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.