Description

1,7-Diazaspiro[4.4]Nonane-2,6-Dione,(S)-(9Ci) is a high-purity, chiral spirocyclic imide compound of significant interest in advanced organic synthesis. This specialized building block is valued for its rigid, three-dimensional structure which is crucial for modulating the physicochemical properties and biological activity of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and as a key intermediate for chiral ligands or catalysts.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated chiral scaffold in the research and synthesis of new drug candidates, especially for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel, structurally complex pesticides and herbicides where its spirocyclic core can impart unique biological activity and stability.
• Asymmetric Synthesis: Acts as a precursor or a chiral auxiliary in asymmetric catalytic reactions to induce stereoselectivity.
• Chemical Biology & Proteomics: Employed as a specialized building block for designing molecular probes and enzyme inhibitors to study biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties due to its rigid structure.
• Academic & Contract Research: A valuable compound for methodological development and discovery chemistry in academic and industrial R&D laboratories.

Basic Information

Product Name	1,7-Diazaspiro[4.4]Nonane-2,6-Dione,(S)-(9Ci)
CAS No.	82399-96-0
Molecular Formula	C7H8N2O2
Molecular Weight	152.15 g/mol
Synonyms	(S)-1,7-Diazaspiro[4.4]nonane-2,6-dione; (S)-Hexahydro-2,6-dioxo-1H,5H-pyrrolo[3,4-c]pyrrole-1-carboxylic acid, 9CI; (S)-2,6-Dioxo-1,7-diazaspiro[4.4]nonane; (S)-Spirocyclic imide; (S)-Hexahydropyrrolo[3,4-c]pyrrole-1,5-dione; (S)-1-Azaspiro[4.4]nonane-2,6-dione derivative; (S)-Chiral spiro imide
EINECS	Contact for details

Quality Control

Our 1,7-Diazaspiro[4.4]Nonane-2,6-Dione,(S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profile is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.