Description

(S)-(1-Methyl-2-Oxo-Ethyl)-Carbamic Acid Benzyl Ester is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound is valued for its role in introducing the (S)-2-aminopropanoic acid (alanine) moiety under controlled conditions, enabling the construction of complex, stereochemically defined molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of peptide-based therapeutics, protease inhibitors, and other active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide drugs, enzyme inhibitors, and novel APIs requiring the (S)-alanine backbone.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid derivative to prevent racemization.
• Protease Inhibitor Development: Serves as a core building block for creating inhibitors targeting specific proteases in drug discovery programs.
• Asymmetric Synthesis: Employed in the preparation of non-natural amino acids and other chiral compounds for medicinal chemistry and chemical biology.
• Bioconjugation & Labeling: The reactive carbonyl and protected amine functionalities allow for selective modification and linker attachment in bioconjugate chemistry.
• Academic & Industrial R&D: A valuable reagent for research in organic methodology development and the study of stereoselective reactions.

Basic Information

Product Name	(S)-(1-Methyl-2-Oxo-Ethyl)-Carbamic Acid Benzyl Ester
CAS No.	82353-55-7
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	(S)-2-[(Benzyloxycarbonyl)amino]propanoic Acid; (S)-N-Cbz-Alanine; (S)-N-Carbobenzoxyalanine; (S)-N-[(Benzyloxy)carbonyl]alanine; (S)-2-[[(Benzyloxy)carbonyl]amino]propanoic Acid; (S)-Alanine, N-[(phenylmethoxy)carbonyl]-; Z-(S)-Ala-OH; Z-L-Alanine
EINECS	Contact for details

Quality Control

Our (S)-(1-Methyl-2-Oxo-Ethyl)-Carbamic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.