Description

13-Ethyl-17-Hydroxy-18,19-Dinorpregna-4,9,11-Trien-20-Yn-3-One 3-Oxime is a high-purity steroid derivative and a key pharmaceutical intermediate of significant commercial interest. Its primary value lies in its role as a critical building block for the synthesis of advanced steroidal active pharmaceutical ingredients (APIs). This compound is essential for manufacturers and research institutions in the pharmaceutical and biotechnology sectors, particularly those developing hormone-based therapies and conducting advanced steroid chemistry research.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of steroidal drugs, including potential progestins and other hormone-related therapeutics.
• Research & Development: Used in academic and industrial R&D laboratories for exploring new chemical entities (NCEs) and novel synthetic pathways in steroid chemistry.
• API Synthesis: Serves as a building block for the production of complex Active Pharmaceutical Ingredients (APIs) requiring a modified sterane backbone.
• Biochemical Research: Employed in studies investigating steroid hormone receptor interactions and metabolic pathways due to its specific structural modifications.
• Process Development: Utilized by process chemists to develop and scale up efficient, cost-effective manufacturing routes for final drug substances.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	13-Ethyl-17-Hydroxy-18,19-Dinorpregna-4,9,11-Trien-20-Yn-3-One 3-Oxime
CAS No.	82332-21-6
Molecular Formula	C22H27NO2
Molecular Weight	337.46 g/mol
Synonyms	13-Ethyl-17-hydroxy-18,19-dinor-17α-pregna-4,9,11-trien-20-yn-3-one oxime; δ9(11)-13-Ethylgon-4-en-17α-ol-3-one 20-yn-3-oxime; Gestodene Impurity; Gestodene Related Compound; 17α-Ethynyl-13-ethyl-17-hydroxygona-4,9,11-trien-3-one oxime; 3-Oximino-13-ethyl-17-hydroxy-18,19-dinorpregna-4,9,11-trien-20-yne
EINECS	Contact for details

Quality Control

Our 13-Ethyl-17-Hydroxy-18,19-Dinorpregna-4,9,11-Trien-20-Yn-3-One 3-Oxime is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.