Description

Pvpdc CAS NO 82246-45-5 is a high-purity specialty chemical compound, also known as Polyvinylpyrrolidone-Dimethylaminopropyl Carbodiimide. This versatile reagent is valued for its role as a zero-length crosslinker and coupling agent, facilitating efficient amide bond formation between carboxylic acids and amines under mild conditions. It is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors who require reliable and effective conjugation chemistry for developing novel therapeutics, diagnostics, and functional polymers.

Application

• Peptide Synthesis & Bioconjugation: A key reagent for coupling peptides, proteins, and other biomolecules to carriers, surfaces, or other molecules in drug development and diagnostic assay production.
• Polymer Modification & Functionalization: Used to introduce specific functional groups or crosslink polymer chains to create hydrogels, smart materials, and coatings with tailored properties.
• Immobilization Chemistry: Facilitates the covalent attachment of enzymes, antibodies, or other ligands to solid supports for chromatography, biosensors, and catalytic applications.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and prodrugs.
• Carbodiimide-Mediated Esterification: Enables the synthesis of esters from carboxylic acids and alcohols, a fundamental reaction in organic and polymer chemistry.
• Research & Development: A staple tool in academic and industrial R&D laboratories for exploring new synthetic pathways and material properties.

Basic Information

Product Name	Pvpdc
CAS No.	82246-45-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Polyvinylpyrrolidone-Dimethylaminopropyl Carbodiimide; PVP-DCC; PVP-Carbodiimide; 1-Cyclohexyl-3-(2-morpholinoethyl)carbodiimide Metho-p-toluenesulfonate PVP Complex; Poly(N-vinyl-2-pyrrolidone)-supported 1-cyclohexyl-3-(2-morpholin-4-ylethyl)carbodiimide; PVP-Supported Carbodiimide; Water-Soluble Carbodiimide Polymer; Polymer-Bound EDC
EINECS	Contact for details

Quality Control

Our Pvpdc is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes rigorous analytical testing, including assay determination and functional group analysis, to meet precise specifications. A comprehensive Certificate of Analysis (COA) documenting purity, identity, and other critical parameters is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and reactivity. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Carbodiimide Content)	≥ 95.0%
Loss on Drying	≤ 5.0%
Solubility	Soluble in water and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.