Description

Calcium Polycarbophil is a high-quality, cross-linked polyacrylic acid derivative supplied as the calcium salt. This pharmaceutical-grade excipient is valued for its exceptional water-absorbing and gel-forming properties, making it a critical component in controlled-release and moisture-managing formulations. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and advanced medical device industries seeking reliable and consistent performance in solid and semi-solid dosage forms.

Application

• Pharmaceutical Tablets & Capsules: As a super-disintegrant to promote rapid tablet breakdown and drug release.
• Controlled-Release Drug Delivery Systems: Functions as a hydrophilic matrix former to modulate the release rate of active pharmaceutical ingredients (APIs).
• Medical & Healthcare Products: Used in formulations for managing diarrhea, constipation, and other gastrointestinal conditions due to its stool-bulking action.
• Nutraceutical & Dietary Supplements: Incorporated into fiber supplements and other health products.
• Topical Gels & Creams: Acts as a stabilizer and viscosity-modifying agent in dermatological preparations.
• Oral Care Products: Used in denture adhesives and other oral mucosal applications for its bioadhesive properties.

Basic Information

Product Name	Calcium Polycarbophil
CAS No.	126040-58-2
Molecular Formula	(C3H4O2)n•xCa
Molecular Weight	Polymeric (Variable)
Synonyms	Calcium Polycarbophil; Polycarbophil Calcium; Calcium Polycarbophil USP; Noveon AA-1; Polycarbophil, Calcium Salt; Acrylic Acid Crosspolymer, Calcium Salt; Carbopol EX-55; Calcium Poly(acrylic acid) Crosspolymer
EINECS	Contact for details

Quality Control

Our Calcium Polycarbophil is manufactured and tested to meet stringent USP-NF (United States Pharmacopeia) monograph standards, ensuring it is suitable for pharmaceutical applications. Each batch undergoes rigorous quality testing for parameters including identification, assay, loss on drying, heavy metals, and microbial limits. A comprehensive Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white, fine powder
Identification (IR)	Conforms
Assay (on dried basis)	98.0 - 102.0%
Loss on Drying	≤ 10.0%
pH (1% Suspension)	4.0 - 6.0
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets USP <61> and <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.