Description

Polacrilin is a synthetic, cross-linked polymer widely recognized for its exceptional ion-exchange capabilities and stability. This material is crucial for formulating controlled-release pharmaceutical products and for use as a disintegrant in solid dosage forms. It is an essential excipient for pharmaceutical manufacturers, research institutions, and developers of advanced drug delivery systems seeking reliable and consistent performance.

Application

• Pharmaceutical Tableting: Primarily used as a super-disintegrant to promote rapid tablet disintegration and drug release.
• Controlled-Release Formulations: Serves as a key matrix-forming agent in extended-release and sustained-release tablets and capsules.
• Ion-Exchange Resin Drug Complexes: Utilized as a carrier for taste-masking bitter drugs or for creating novel drug-resin complexes for modified release.
• Stabilizing Agent: Can be employed to stabilize active pharmaceutical ingredients (APIs) that are sensitive to moisture or incompatible with other excipients.
• Food & Nutraceutical Supplements: Used in the formulation of dietary supplements and vitamin tablets where rapid disintegration is required.
• Veterinary Pharmaceuticals: Applied in the development of palatable and effective solid dosage forms for animal health.

Basic Information

Product Name	Polacrilin
CAS No.	54182-62-6
Molecular Formula	(C5H5NO)n • (C4H6O2)m
Molecular Weight	Varies (Polymer)
Synonyms	Polacrilin Potassium; Amberlite™ IRP88; Methacrylic Acid Divinylbenzene Copolymer; Poly(methacrylic acid-co-divinylbenzene); Potassium Polacrilin; Eudragit® (related polymer family); Ion Exchange Resin, Weakly Acidic; NF Polacrilin
EINECS	Contact for details

Quality Control

Our Polacrilin is manufactured and tested to meet stringent pharmaceutical-grade standards. Quality assurance protocols ensure compliance with relevant pharmacopoeial monographs, including USP-NF. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, particle size distribution, swelling capacity, and heavy metal limits, guaranteeing batch-to-batch consistency for your critical formulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to protect the product from atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white fine powder
Identification (IR)	Conforms to standard
Assay (as Potassium Polacrilin)	NLT 95.0%
Loss on Drying	NMT 5.0%
Particle Size Distribution	Specified per grade
Swelling Capacity	Specified per grade
Heavy Metals	NMT 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.