Description

Crospovidone is a cross-linked, water-insoluble polymer of N-vinyl-2-pyrrolidone, widely recognized as a highly effective super-disintegrant. Its primary value lies in its exceptional ability to rapidly absorb water and swell, creating a porous structure that facilitates the quick disintegration and dissolution of solid dosage forms. This makes it an indispensable excipient for manufacturers in the pharmaceutical and nutraceutical industries seeking to enhance the bioavailability and performance of tablets and capsules.

Application

• Pharmaceutical Tablets & Capsules: As a super-disintegrant in immediate-release and fast-dissolving oral solid dosage forms.
• Nutraceutical & Dietary Supplements: To improve the disintegration rate of vitamin, mineral, and herbal supplement tablets.
• Orally Disintegrating Tablets (ODTs): A key component for achieving rapid in-mouth disintegration without water.
• Effervescent Tablets: Used in conjunction with effervescent agents to control and enhance the disintegration process.
• Suspension Stabilizer: Acts as a suspending agent to improve the physical stability of liquid and semi-solid formulations.
• Taste Masking Carrier: Employed to adsorb and mask unpleasant-tasting active ingredients in oral formulations.

Basic Information

Product Name	Crospovidone
CAS No.	25249-54-1
Molecular Formula	(C6H9NO)n
Molecular Weight	~1,000,000 (Typical average)
Synonyms	Cross-linked PVP; Crospovidon; Polyvinylpolypyrrolidone; PVPP; Insoluble Polyvinylpyrrolidone; 1-Ethenyl-2-pyrrolidinone homopolymer, cross-linked; E1202; Kollidon CL
EINECS	246-770-6

Quality Control

Our Crospovidone is manufactured and tested to meet stringent global pharmacopoeial standards, including USP-NF and Ph. Eur. specifications. Every batch undergoes rigorous quality testing for parameters such as particle size distribution, water absorption capacity, and residue on ignition. A comprehensive Certificate of Analysis (COA) is provided with each shipment to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from excessive heat and moisture. Under these conditions, the product remains stable for extended periods.

Specification

Item	Specification
Appearance	White or yellowish-white powder
Identification (IR)	Conforms
pH (10% suspension)	5.0 - 8.0
Water Absorption	≥ 5.0 ml/g
Loss on Drying	≤ 6.0 %
Sulphated Ash	≤ 1.0 %
Nitrogen Content	11.0 - 12.8 %
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.