Description

1-(5-Nitropyridin-2-Yl)Piperazine is a high-purity, specialized heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique nitropyridine-piperazine scaffold enables precise molecular modifications. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and antimicrobials.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging its bioactive nitropyridine moiety.
• Ligand Synthesis: Employed in organometallic chemistry and catalysis for creating complex chelating ligands.
• Material Science Research: Serves as a building block for advanced polymers and functional materials with specific electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a functionalized pyridine-piperazine hybrid structure.

Basic Information

Product Name	1-(5-Nitropyridin-2-Yl)Piperazine
CAS No.	82205-58-1
Molecular Formula	C9H12N4O2
Molecular Weight	208.22 g/mol
Synonyms	1-(5-Nitropyridin-2-yl)piperazine; 2-(1-Piperazinyl)-5-nitropyridine; 5-Nitro-2-piperazin-1-ylpyridine; 5-Nitro-2-(piperazin-1-yl)pyridine; 1-(5-Nitro-2-pyridinyl)piperazine; Piperazine, 1-(5-nitro-2-pyridinyl)-; 82205-58-1; 1-(5-Nitropyridin-2-Yl)Piperazine
EINECS	Contact for details

Quality Control

Our 1-(5-Nitropyridin-2-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.