Description

3-Amino-6-(4-Methylpiperazin-1-yl)pyridine Trihydrochloride is a high-purity, multi-functional organic building block of significant importance in advanced chemical synthesis. Its core value lies in its dual functionality, serving as a key intermediate for the development of complex heterocyclic compounds, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in medicinal chemistry, agrochemical development, and material science who require reliable, high-quality intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides with specific biological activity.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and cellular pathways.
• Ligand Synthesis for Catalysis: Acts as a starting material for synthesizing complex ligands used in homogeneous catalysis.
• Material Science Research: Investigated as a monomer or additive for creating functional polymers and advanced organic materials.

Basic Information

Item	Details
Product Name	3-Amino-6-(4-Methylpiperazin-1-yl)pyridine Trihydrochloride
CAS No.	82205-57-0
Molecular Formula	C10H17N5 • 3HCl
Molecular Weight	328.66 g/mol (free base: 207.28 g/mol)
Synonyms	3-Amino-6-(4-methyl-1-piperazinyl)pyridine trihydrochloride; 3-Amino-6-(N-methylpiperazino)pyridine trihydrochloride; 6-(4-Methylpiperazin-1-yl)pyridin-3-amine trihydrochloride; 3-Amino-6-(4-methylpiperazino)pyridine hydrochloride (1:3); 82205-57-0; 3-Amino-6-(4-methylpiperazin-1-yl)pyridine HCl salt
EINECS	Contact for details

Quality Control

Our 3-Amino-6-(4-Methylpiperazin-1-yl)pyridine Trihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.