Description

Estradiol-17-Stearate is a long-chain fatty acid ester derivative of the natural estrogen, estradiol. This chemical modification enhances its lipophilicity, which can influence its pharmacokinetic profile, including absorption and sustained release properties. It is primarily utilized in the pharmaceutical and life science research sectors for the development and study of hormone-based therapies and delivery systems. The compound is of significant interest for applications requiring controlled hormone release or specialized formulation strategies.

Application

• Pharmaceutical Intermediates: Serves as a key synthetic intermediate or prodrug in the development of estrogen-based hormone replacement therapies (HRT).
• Research & Development: Used in biochemical and pharmacological research to study estrogen receptor interactions, metabolic pathways, and the effects of esterification on hormone activity.
• Controlled-Release Formulations: Its lipophilic nature makes it a candidate for incorporation into sustained-release drug delivery systems, such as implants or microspheres.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Veterinary Pharmaceuticals: Potential use in the formulation of hormonal treatments for animals in veterinary medicine.

Basic Information

Product Name	Estradiol-17-Stearate
CAS No.	82205-00-3
Molecular Formula	C₃₆H₆₀O₃
Molecular Weight	552.87 g/mol
Synonyms	Estradiol 17-stearate; 17β-Estradiol 17-stearate; Estra-1,3,5(10)-triene-3,17β-diol 17-octadecanoate; 3-Hydroxy-19-norpregna-1,3,5(10)-trien-20-yn-17-yl stearate; NSC 17591
EINECS	Contact for details

Quality Control

Our Estradiol-17-Stearate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-grade standards suitable for research and pharmaceutical applications. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; appropriate handling procedures should be followed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.