Description

4'-Hydroxybutobarbitone is a specialized barbiturate derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial intermediate or reference standard for the synthesis and analytical characterization of related therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology, drug metabolism studies, and the development of novel sedative-hypnotic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex barbiturate-based active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, validation, and quality control (HPLC, GC-MS) in pharmaceutical laboratories to ensure product purity and compliance.
• Biochemical Research: Employed in in vitro studies to investigate the mechanism of action, metabolism, and structure-activity relationships (SAR) of barbiturates.
• Metabolite Studies: Serves as a reference compound for identifying and quantifying metabolic products in pharmacokinetic and toxicological research.
• Controlled Substance Analysis: Used as a calibration standard in forensic and regulatory laboratories for the accurate identification of controlled substances.

Basic Information

Product Name	4'-Hydroxybutobarbitone
CAS No.	82168-60-3
Molecular Formula	C10H14N2O4
Molecular Weight	226.23 g/mol
Synonyms	4'-Hydroxybutobarbital; 5-Butyl-5-(4-hydroxybutyl)barbituric acid; 5-Butyl-5-(4-hydroxybutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; Butobarbitone 4'-hydroxy derivative; 4'-OH-Butobarbital
EINECS	Contact for details

Quality Control

Our 4'-Hydroxybutobarbitone is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; appropriate handling procedures should be followed to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.