Description

3-Trimethylsilylbenzonitrile is a versatile organosilicon compound featuring a benzonitrile core functionalized with a trimethylsilyl group. This unique structure makes it a valuable synthetic intermediate and protecting group reagent in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring silyl-protected aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the nitrile and silyl groups introduce specific bioactivity.
• Material Science Precursor: Serves as a monomer or modifying agent in the production of specialty polymers and silicon-based advanced materials.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organocatalysts.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the trimethylsilyl group and for cyano-group transformations in multi-step synthetic routes.
• Research & Development: Essential tool compound in academic and industrial R&D labs for methodology development and exploring new chemical spaces.

Basic Information

Product Name	3-Trimethylsilylbenzonitrile
CAS No.	82142-18-5
Molecular Formula	C10H13NSi
Molecular Weight	175.31 g/mol
Synonyms	m-(Trimethylsilyl)benzonitrile; 3-(Trimethylsilyl)benzonitrile; Benzonitrile, 3-(trimethylsilyl)-; (3-Cyanophenyl)trimethylsilane; Trimethyl(3-cyanophenyl)silane; m-Cyanophenyltrimethylsilane; TMS-benzonitrile (meta)
EINECS	Contact for details

Quality Control

Our 3-Trimethylsilylbenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC and GC analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.