Description

2-Bromo-4,6-Diphenylnicotinonitrile is a specialized brominated and phenyl-substituted pyridine derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its molecular architecture makes it a critical building block for constructing complex heterocyclic frameworks, enabling the development of novel compounds with targeted properties. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its heterocyclic core.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions due to the reactive bromine atom.
• Academic & Contract Research: Essential for methodological studies and library synthesis in academic laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	2-Bromo-4,6-Diphenylnicotinonitrile
CAS No.	82127-26-2
Molecular Formula	C18H11BrN2
Molecular Weight	335.20 g/mol
Synonyms	2-Bromo-4,6-diphenyl-3-pyridinecarbonitrile; 3-Cyano-2-bromo-4,6-diphenylpyridine; 4,6-Diphenyl-2-bromonicotinonitrile; Nicotinonitrile, 2-bromo-4,6-diphenyl-; 2-Bromo-4,6-diphenyl-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,6-Diphenylnicotinonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and relevant specifications is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.