Description

17 α-Iodovinylestradiol CAS NO 82123-96-4 is a high-purity, synthetic steroidal compound featuring a unique iodovinyl modification at the 17-alpha position. This structural modification is of significant interest in advanced pharmaceutical research and development, particularly for creating novel molecular probes and potential therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in endocrinology, oncology, and radiopharmaceutical studies. The compound's defined structure makes it a valuable intermediate for specialized synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel steroidal drugs and targeted therapeutic agents.
• Research & Development: Used as a reference standard and active compound in biochemical and pharmacological research, particularly in hormone receptor studies.
• Radiopharmaceutical Precursor: The iodine atom provides a potential site for radioiodination, making it a candidate precursor for developing diagnostic imaging agents.
• Chemical Synthesis: Employed in organic synthesis to introduce steroidal frameworks with specific halogenated functionalities.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of estrogen derivatives.

Basic Information

Product Name	17 α-Iodovinylestradiol
CAS No.	82123-96-4
Molecular Formula	C20H25IO2
Molecular Weight	424.32 g/mol
Synonyms	17α-Iodovinylestradiol; Estra-1,3,5(10)-triene-3,17-diol, 17-[(1E)-2-iodoethenyl]-; (17α)-17-[(E)-2-Iodovinyl]estra-1,3,5(10)-triene-3,17-diol; 17α-(2-Iodovinyl)estradiol; Iodovinyl Estradiol
EINECS	Contact for details

Quality Control

Our 17 α-Iodovinylestradiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.