Description

tert-Butyl(Dimethyl)Silyl 3-([tert-Butyl(Dimethyl)Silyl]Oxy)Propanoate is a specialized organosilicon reagent featuring dual silyl protecting groups. This compound is critical for synthetic chemists requiring selective protection of carboxylic acid and alcohol functionalities in complex multi-step syntheses. It is primarily utilized in the research and development of pharmaceuticals, agrochemicals, and advanced organic materials where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for protecting sensitive functional groups during the synthesis of active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the protection of carboxyl groups in solid-phase and solution-phase peptide synthesis.
• Natural Product Synthesis: Enables the selective manipulation of polyfunctional molecules in the total synthesis of complex natural products.
• Agrochemical Research: Serves as a precursor or protecting agent in the development of novel herbicides, fungicides, and insecticides.
• Material Science: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored properties.
• Process Chemistry Development: Facilitates scalable and efficient synthetic routes in pilot plant and manufacturing settings.

Basic Information

Product Name	tert-Butyl(Dimethyl)Silyl 3-([tert-Butyl(Dimethyl)Silyl]Oxy)Propanoate
CAS No.	82112-30-9
Molecular Formula	C15H34O3Si2
Molecular Weight	318.60 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]propanoic acid tert-butyldimethylsilyl ester; TBDMS 3-(TBDMSoxy)propanoate; Bis-TBDMS Propanoate Ester; 3-(tert-Butyldimethylsiloxy)propionic acid tert-butyldimethylsilyl ester; 82112-30-9; tert-Butyldimethylsilyl 3-(tert-butyldimethylsiloxy)propionate; Propanoic acid, 3-[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (1,1-dimethylethyl)dimethylsilyl ester
EINECS	Contact for details

Quality Control

Our production of tert-Butyl(Dimethyl)Silyl 3-([tert-Butyl(Dimethyl)Silyl]Oxy)Propanoate adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.