Description

n-Methoxycarbonylphenylalanylglycine 4-Nitrophenyl Ester CAS NO 82080-92-0 is a specialized peptide derivative and activated ester, widely utilized as a key building block in organic synthesis and peptide chemistry. Its core value lies in its role as an efficient acylating agent, facilitating the controlled formation of amide bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for developing novel peptide-based therapeutics, prodrugs, and advanced biomaterials.

Application

• Peptide Synthesis Intermediate: Acts as a crucial acyl donor in solid-phase and solution-phase peptide synthesis for coupling specific amino acid sequences.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, prodrugs, and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a reactive handle for labeling peptides, proteins, and other biomolecules with reporter groups or functional moieties.
• Protease Substrate Analog: Employed in biochemical assays to study enzyme kinetics and inhibition, particularly for proteolytic enzymes.
• Material Science: Utilized in the development of novel polymeric materials and hydrogels with peptide-based crosslinkers.
• Academic & Industrial Research: A valuable tool compound for methodological development in organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	n-Methoxycarbonylphenylalanylglycine 4-Nitrophenyl Ester
CAS No.	82080-92-0
Molecular Formula	C20H21N3O7
Molecular Weight	415.40 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-L-phenylalanylglycine 4-nitrophenyl ester; Z-Phe-Gly-ONp; Cbz-Phe-Gly-ONp; N-Carbobenzoxy-L-phenylalanylglycine p-nitrophenyl ester; Benzyloxycarbonylphenylalanylglycine p-nitrophenyl ester; (S)-2-(((Benzyloxy)carbonyl)amino)-3-phenyl-N-(4-nitrophenoxy)propanamide; Z-Phenylalanylglycine p-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our n-Methoxycarbonylphenylalanylglycine 4-Nitrophenyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and potency. Keep the container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.