Description

Methyl 5-Chloro-2-Methoxynicotinate is a high-purity, versatile nicotinate derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized pyridine core essential for constructing complex molecules with targeted biological activity. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for synthesizing functionalized polymers and organic electronic materials.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	Methyl 5-Chloro-2-Methoxynicotinate
CAS No.	82060-51-3
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	5-Chloro-2-methoxynicotinic acid methyl ester; Methyl 5-chloro-2-methoxy-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid, 5-chloro-2-methoxy-, methyl ester; 5-Chloro-2-methoxypyridine-3-carboxylic acid methyl ester; 82060-51-3; Methyl 5-chloro-2-methoxypyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-2-Methoxynicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.