Description

(S)-tert-Butyl 2,6-Diaminohexanoate Dihydrochloride is a high-purity, enantiomerically pure chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules where stereochemical integrity is paramount, ensuring the efficacy and safety of the final active pharmaceutical ingredient. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing peptide-based therapeutics and other advanced drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide drugs, enzyme inhibitors, and other bioactive molecules.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and targeted drug delivery systems due to its dual amino functionality.
• Protecting Group Strategy: The tert-butyl ester group serves as a valuable protecting group in multi-step organic syntheses, particularly in peptide chemistry.
• Asymmetric Synthesis: Employed as a starting material or building block for the preparation of other enantiomerically pure compounds.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and novel therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-tert-Butyl 2,6-Diaminohexanoate Dihydrochloride
CAS No.	82004-77-1
Molecular Formula	C10H24Cl2N2O2
Molecular Weight	275.22 g/mol
Synonyms	(S)-2,6-Bis(tert-butoxycarbonylamino)hexanoic acid dihydrochloride; (S)-Boc-Lys(Boc)-OH · 2HCl; H-Lys(Boc)-OtBu · 2HCl; (S)-tert-Butyl N2,N6-bis(tert-butoxycarbonyl)-L-lysinate dihydrochloride; Nα,Nε-Bis-Boc-L-lysine tert-butyl ester dihydrochloride; Boc-Lys(Boc)-OtBu · 2HCl; L-Lysine, N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethylethyl ester, hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 2,6-Diaminohexanoate Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.