Description

3-Hydroxydeoxyartemisinin is a key derivative and synthetic intermediate of artemisinin, a sesquiterpene lactone with a peroxide bridge. This compound matters for its role in the research and development of novel antimalarial agents and other bioactive molecules, offering a versatile scaffold for chemical modification. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel artemisinin derivatives with potential antimalarial, anticancer, or antiviral activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to understand and optimize the pharmacophore of artemisinin-based drugs.
• Reference Standard: Serves as an analytical standard in quality control and method development for artemisinin-related compound analysis.
• Biochemical Research: Employed in studies investigating the mechanism of action of artemisinin and its derivatives against Plasmodium parasites.
• Fine Chemical Synthesis: Utilized as a specialized starting material for the production of high-value, complex organic molecules.

Basic Information

Product Name	3-Hydroxydeoxyartemisinin
CAS No.	82003-85-8
Molecular Formula	C15H24O4
Molecular Weight	268.35 g/mol
Synonyms	3-Hydroxydeoxyartemisinin; 3-Hydroxy-11-epi-artemisinin; 3α-Hydroxy-11-epi-artemisinin; 3-Hydroxy-11-epideoxyartemisinin; Deoxyartemisinin-3-ol; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol
EINECS	Contact for details

Quality Control

Our 3-Hydroxydeoxyartemisinin is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; prolonged exposure to air and light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.