Description

3-Bromo-1-Methylpyridin-2(1H)-One is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its reactive bromine substituent, which enables efficient functionalization and serves as a key intermediate for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridone or pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive site for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Cross-Coupling Reactions: Acts as a competent substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) for carbon-carbon bond formation.
• Nucleophilic Substitution Scaffold: The bromine atom is readily displaced by various nucleophiles, facilitating the introduction of amines, alkoxides, and thiols.

Basic Information

Item	Detail
Product Name	3-Bromo-1-Methylpyridin-2(1H)-One
CAS No.	81971-38-2
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	3-Bromo-1-methyl-2(1H)-pyridinone; 3-Bromo-1-methyl-2-pyridone; 3-Bromo-1-methylpyridin-2-one; 1-Methyl-3-bromo-2-pyridone; 3-Bromo-1-methyl-1H-pyridin-2-one; 3-Brom-1-methyl-2(1H)-pyridon; 3-Bromo-1-methyl-2-hydroxypyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-1-Methylpyridin-2(1H)-One is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.