Description

n-Chloroethylnitrosourea Asparaginamide is a specialized alkylating agent derivative, designed for targeted research and development applications. This compound is valued for its potential as a key intermediate in the synthesis of novel therapeutic agents, particularly in oncology research. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in developing next-generation treatments.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of experimental anti-cancer compounds and targeted therapies.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of alkylation and DNA interaction for potential chemotherapeutic applications.
• Bioconjugation Studies: Employed in the development of antibody-drug conjugates (ADCs) or other targeted drug delivery systems due to its reactive functional groups.
• Academic & Institutional R&D: A key reagent for universities and research institutes exploring novel nitrosourea derivatives and their biological activities.
• Process Development: Used by fine chemical manufacturers for scaling up synthetic routes and optimizing production processes for advanced pharmaceutical ingredients (APIs).
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Product Name	n-Chloroethylnitrosourea Asparaginamide
CAS No.	81965-31-3
Molecular Formula	C7H12ClN5O4
Molecular Weight	265.65 g/mol
Synonyms	1-(2-Chloroethyl)-3-(4-aminocarbonyl-2-aminobutyryl)-1-nitrosourea; NSC 409962; Chloroethylnitrosourea-Asparaginamide; CENU-Asparaginamide; 1-(2-Chloroethyl)-3-[(2S)-2-amino-4-carbamoylbutanoyl]-1-nitrosourea; N-(2-Chloroethyl)-N'-[(2S)-2-amino-4-carbamoylbutanoyl]-N-nitrosourea; L-Asparaginamide, N-[N'-(2-chloroethyl)-N'-nitrosocarbamoyl]-
EINECS	Contact for details

Quality Control

Our n-Chloroethylnitrosourea Asparaginamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep the container in a dry, cool, and well-ventilated area, separate from incompatible materials. For long-term stability, desiccate if necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.