Description

Octanoylprimaquine is a synthetic derivative of the antimalarial drug primaquine, modified with an octanoyl group to potentially alter its pharmacokinetic profile. This compound is of significant interest in pharmaceutical research and development for creating novel therapeutic agents. It serves as a key intermediate for medicinal chemists and researchers focused on developing new treatments for parasitic diseases and exploring prodrug strategies.

Application

• Pharmaceutical Intermediate: Primary use as a building block in the synthesis of novel antimalarial drug candidates and prodrugs.
• Medicinal Chemistry Research: Critical for structure-activity relationship (SAR) studies to optimize the efficacy and safety profiles of primaquine analogs.
• Prodrug Development: Investigation for its potential to improve the bioavailability, metabolic stability, or targeted delivery of primaquine-based therapies.
• Biochemical Research: Used as a reference standard or probe in studies investigating the mechanism of action of 8-aminoquinoline compounds.
• API Synthesis: Serves as a precursor in the controlled synthesis of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical studies.

Basic Information

Product Name	Octanoylprimaquine
CAS No.	81947-79-7
Molecular Formula	C26H39N3O3
Molecular Weight	441.61 g/mol
Synonyms	N-Octanoylprimaquine; Primaquine Caprylate; 1-Octanoylprimaquine; 8-[(4-Amino-1-methylbutyl)amino]-6-methoxyquinoline N-Octanoate; N-Capryloylprimaquine; N-(8-[(4-Amino-1-methylbutyl)amino]-6-methoxyquinolin-2-yl)octanamide
EINECS	Contact for details

Quality Control

Our Octanoylprimaquine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.