Description

1-Phenyl-1-(2-Pyridinyl)-2-(1H-1,2,4-Triazol-1-Yl)Ethanol is a high-purity, non-racemic chiral building block and synthetic intermediate of significant commercial interest. Its complex heterocyclic structure, featuring pyridine and triazole moieties, makes it a valuable precursor in the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel antifungal, antiviral, and other therapeutic agents.
• Agrochemical Research: Used as a core structure for developing new generation fungicides and plant growth regulators.
• Asymmetric Synthesis: Serves as a sophisticated chiral auxiliary or ligand precursor in catalytic asymmetric reactions.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Biochemical Research: Utilized in academic and industrial R&D for studying enzyme inhibition and receptor-ligand interactions.
• Material Science: Potential precursor for functionalized polymers or metal-organic frameworks (MOFs) with specialized properties.

Basic Information

Product Name	1-Phenyl-1-(2-Pyridinyl)-2-(1H-1,2,4-Triazol-1-Yl)Ethanol
CAS No.	81854-16-2
Molecular Formula	C₁₅H₁₄N₄O
Molecular Weight	266.30 g/mol
Synonyms	α-(2-Pyridyl)-α-phenyl-1H-1,2,4-triazole-1-ethanol; (RS)-1-Phenyl-1-(pyridin-2-yl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol; 1-Phenyl-1-(2-pyridyl)-2-(1,2,4-triazol-1-yl)ethanol; 2-(1H-1,2,4-Triazol-1-yl)-1-phenyl-1-(2-pyridinyl)ethanol; (Rac)-1-Phenyl-1-(pyridin-2-yl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 1-Phenyl-1-(2-Pyridinyl)-2-(1H-1,2,4-Triazol-1-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and agrochemical synthesis. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Enantiomeric excess)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.