Description

1,4-Dioxaspiro[4.5]Dec-6-Ene, 8-Methyl- is a specialized spirocyclic acetal derivative, serving as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique bridged-ring structure makes it a critical building block for constructing complex molecular architectures, particularly in the synthesis of pharmaceuticals and fine chemicals. This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, including potential central nervous system (CNS) agents and antiviral compounds.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its spirocyclic framework for enhanced biological activity.
• Fine Chemical Production: Serves as a building block for fragrances, flavors, and other specialty chemicals requiring specific stereochemistry.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties.
• Academic & R&D Laboratories: Employed in methodological studies and the development of new synthetic routes involving acetal protection and spiroannulation reactions.
• Catalyst Ligand Framework: Its structure can be functionalized to create novel ligands for asymmetric catalysis.

Basic Information

Item	Detail
Product Name	1,4-Dioxaspiro[4.5]Dec-6-Ene, 8-Methyl-
CAS No.	81842-08-2
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	8-Methyl-1,4-dioxaspiro[4.5]dec-6-ene; 8-Methyl-1,4-dioxaspiro[4.5]-6-decene; 6,7-Dihydro-8-methyl-1,4-dioxaspiro[4.5]dec-6-ene; 8-Methyl-6,7-dihydro-1,4-dioxaspiro[4.5]dec-6-ene; Spiro[1,3-dioxolane-2,1'-cyclohex-4'-ene], 4'-methyl-; 4'-Methylspiro[1,3-dioxolane-2,1'-cyclohex-4'-ene]; (6-Methyl-1,4-dioxaspiro[4.5]dec-7-ene) (isomer reference).
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.5]Dec-6-Ene, 8-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.