Description

(1β,2α,4α,5β,6β)-3,8-Dioxatricyclo[3.2.1.02,4]Octane-6-Carboxylic Acid Methyl Ester is a high-purity, specialized bicyclic lactone derivative with a complex, rigid molecular architecture. This compound serves as a critical chiral building block and advanced intermediate in sophisticated organic syntheses, where its unique stereochemistry and functional groups enable precise molecular construction. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral applications.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides with specific stereochemical requirements for biological activity.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a test substrate in the development of new chiral catalysts and methodologies.
• Natural Product & Fragrance Chemistry: Serves as a core structural motif for the synthesis of complex natural products and high-value aroma chemicals.
• Material Science Research: Investigated as a monomer for creating novel polymers with specific thermal or mechanical properties derived from its rigid bicyclic structure.
• Academic & Institutional Research: Utilized in university and institutional labs for studies in synthetic organic chemistry and stereochemistry.

Basic Information

Product Name	(1β,2α,4α,5β,6β)-3,8-Dioxatricyclo[3.2.1.02,4]Octane-6-Carboxylic Acid Methyl Ester
CAS No.	81800-81-9
Molecular Formula	C9H10O4
Molecular Weight	182.17 g/mol
Synonyms	Methyl (1R,2S,4S,5R,6R)-3,8-dioxatricyclo[3.2.1.02,4]octane-6-carboxylate; 6-Carbomethoxy-2,7-dioxabicyclo[2.2.1]heptane; Methyl 3,8-dioxatricyclo[3.2.1.02,4]octane-6-carboxylate; Bicyclic Lactone Methyl Ester; 81800-81-9; (1R,2S,4S,5R,6R)-rel-3,8-Dioxatricyclo[3.2.1.02,4]octane-6-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of our (1β,2α,4α,5β,6β)-3,8-Dioxatricyclo[3.2.1.02,4]Octane-6-Carboxylic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.