Description

(2α,4α,6α)-1α,5α-Dimethyl-3,8-Dioxatricyclo[3.2.1.02,4]Octane-6-Carboxylic Acid Methyl Ester is a high-purity, synthetically derived chiral compound featuring a complex tricyclic oxa-cage structure. This molecule is valued as a critical advanced pharmaceutical intermediate and a versatile building block in asymmetric synthesis for the development of novel active ingredients. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams requiring precise stereochemistry and high chemical purity to drive innovation in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and anti-inflammatory pathways.
• Asymmetric Catalysis: Serves as a precursor or ligand for developing novel chiral catalysts used in stereoselective transformations.
• Medicinal Chemistry Research: Utilized as a rigid, three-dimensional scaffold for constructing compound libraries in structure-activity relationship (SAR) studies.
• Fragrance & Flavor Chemistry: Potential use as an intermediate for synthesizing unique, high-value aroma chemicals with complex olfactory profiles.
• Agrochemical Synthesis: Intermediate in the research and development of new-generation pesticides and herbicides with specific stereochemical requirements.
• Academic & Institutional Research: Used in methodological studies exploring new reactions involving strained oxa-cage systems.

Basic Information

Product Name	(2α,4α,6α)-1α,5α-Dimethyl-3,8-Dioxatricyclo[3.2.1.02,4]Octane-6-Carboxylic Acid Methyl Ester
CAS No.	81763-42-0
Molecular Formula	C11H16O4
Molecular Weight	212.24 g/mol
Synonyms	Methyl (2a,4a,6a)-1a,5-dimethyl-3,8-dioxatricyclo[3.2.1.02,4]octane-6-carboxylate; 1a,5a-Dimethyl-3,8-dioxatricyclo[3.2.1.02,4]octane-6a-carboxylic acid methyl ester; Methyl 1,5-dimethyl-3,8-dioxatricyclo[3.2.1.02,4]octane-6-carboxylate; Oxa-cage methyl ester; Tricyclic oxa-cage ester; CAS 81763-42-0
EINECS	Contact for details

Quality Control

Every batch of our (2α,4α,6α)-1α,5α-Dimethyl-3,8-Dioxatricyclo[3.2.1.02,4]Octane-6-Carboxylic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available for every shipment. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.