Description

Methyl (S)-(+)-3-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-cis-2-Propenoate is a high-purity chiral building block and key synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functionalized dioxolane-protected diol structure make it indispensable for constructing complex, optically active molecules. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where biological activity is highly dependent on molecular configuration.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor for chiral ligands and catalysts used in stereoselective transformations.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural products, flavors, and fragrances requiring precise stereocontrol.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	Methyl (S)-(+)-3-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-cis-2-Propenoate
CAS No.	81703-94-8
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(S)-(+)-Methyl 3-(2,2-Dimethyl-1,3-dioxolan-4-yl)-cis-acrylate; (4S)-3-(2,2-Dimethyl-1,3-dioxolan-4-yl)-2-propenoic Acid Methyl Ester; Methyl (S)-3-(2,2-Dimethyl-1,3-dioxolan-4-yl)acrylate; (S)-Methyl 3-(2,2-Dimethyl-1,3-dioxolan-4-yl)propenoate; (S)-Methyl 3-(2,2-Dimethyl-1,3-dioxolan-4-yl)acrylate; cis-Methyl (S)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)acrylate
EINECS	Contact for details

Quality Control

Our production of Methyl (S)-(+)-3-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-cis-2-Propenoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation [α]D20	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.