Description

Methyl (S)-(+)-3-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-trans-2-Propenoate is a high-value chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its core value proposition lies in its stereochemically defined structure, which is critical for the production of enantiomerically pure compounds, particularly in the pharmaceutical sector. This product is essential for research chemists and process development scientists in industries such as pharmaceuticals, agrochemicals, and fine chemicals who require high-purity, optically active intermediates for asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and insecticides where specific stereochemistry impacts biological activity.
• Fine Chemical Manufacturing: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances requiring precise stereocontrol.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, particularly in studies involving stereoselective reactions like Michael additions or cyclizations.
• Material Science Precursor: Potential use in the synthesis of chiral polymers or advanced materials with specific optical properties.

Basic Information

Product Name	Methyl (S)-(+)-3-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-trans-2-Propenoate
CAS No.	81703-93-7
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(S)-(+)-3-(2,2-Dimethyl-1,3-dioxolan-4-yl)-trans-2-propenoic acid methyl ester; Methyl (S)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)acrylate; (S)-Methyl 3-(2,2-dimethyl-1,3-dioxolan-4-yl)propenoate; (S)-Methyl 3-(2,2-dimethyl-1,3-dioxolan-4-yl)acrylate; (4S)-3-(2,2-Dimethyl-1,3-dioxolan-4-yl)-2-propenoic acid methyl ester; (S)-Methyl 3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-propenoate; Acrylic acid, 3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl (S)-(+)-3-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-trans-2-Propenoate is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and GC/HPLC for chemical purity assessment. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.