Description

[1S,1'S,4S,5R,(+)]-3',3'A,4',5',6',6'A-Hexahydro-1'α,3'Aα,4'α,6'Aα-Tetramethylspiro[2,6-Dioxabicyclo[3.1.0]Hexane-4,2'(1'H)-Pentalene]-3-One is a high-purity, stereochemically defined spirocyclic compound with a complex bicyclic structure. This compound serves as a critical chiral intermediate or building block in advanced organic synthesis, particularly for the development of pharmaceuticals and specialty chemicals. It is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries who require precise molecular architecture for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used as a building block for creating advanced, stereospecific pesticides and herbicides with enhanced efficacy.
• Asymmetric Catalysis: Potential ligand precursor or chiral auxiliary in catalytic systems designed for enantioselective synthesis.
• Fine Chemical Production: Serves as a starting material for synthesizing complex fragrance molecules, flavors, or other high-value specialty chemicals.
• Academic & Industrial R&D: Valuable reference standard and reagent for methodological development in organic chemistry and total synthesis projects.
• Material Science Research: Investigated as a monomer or precursor for novel polymers with specific stereochemical properties.

Basic Information

Product Name	[1S,1'S,4S,5R,(+)]-3',3'A,4',5',6',6'A-Hexahydro-1'α,3'Aα,4'α,6'Aα-Tetramethylspiro[2,6-Dioxabicyclo[3.1.0]Hexane-4,2'(1'H)-Pentalene]-3-One
CAS No.	81674-82-0
Molecular Formula	C₁₇H₂₄O₃
Molecular Weight	276.37 g/mol
Synonyms	(+)-Spiro[2,6-Dioxabicyclo[3.1.0]hexane-4,2'(1'H)-Pentalene]-3-One derivative; 1'α,3'Aα,4'α,6'Aα-Tetramethylspiro compound; Hexahydro-tetramethylspiro dioxabicyclohexane pentalenone; CAS 81674-82-0; (4S,5R)-4,5-Dimethyl-2,8-dioxatricyclo[7.1.0.0³,⁶]decane-3,9-dione (related core structure); Spirocyclic lactone derivative; Chiral spiroketal
EINECS	Contact for details

Quality Control

Our production of [1S,1'S,4S,5R,(+)]-3',3'A,4',5',6',6'A-Hexahydro-1'α,3'Aα,4'α,6'Aα-Tetramethylspiro[2,6-Dioxabicyclo[3.1.0]Hexane-4,2'(1'H)-Pentalene]-3-One adheres to strict cGMP and ISO 9001 standards, ensuring batch-to-batch consistency and high chemical purity. Every lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and can be customized to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.