Description

Trifluoroacetyl-Tris(Trimethylsilyl)Silane CAS NO 81671-46-7 is a highly specialized organosilicon reagent featuring a unique trifluoroacetyl group. This compound is valued for its role as a versatile silylating agent and a key building block in advanced synthetic chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel silicon-containing molecules and fine chemicals.

Application

• Advanced Pharmaceutical Intermediates: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those requiring silicon or fluorine incorporation for enhanced bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its unique structure can contribute to improved efficacy and environmental profile.
• Materials Science Research: Acts as a key monomer or cross-linking agent in the development of specialty silicones, silicon-based polymers, and advanced hybrid materials with tailored properties.
• Organic Synthesis Reagent: Employed as a powerful silylating and protecting agent in multi-step synthetic routes for sensitive or complex organic molecules.
• Surface Modification: Utilized to functionalize silica, glass, or other inorganic surfaces, imparting specific chemical properties for coatings or composite materials.

Basic Information

Product Name	Trifluoroacetyl-Tris(Trimethylsilyl)Silane
CAS No.	81671-46-7
Molecular Formula	C11H27F3OSi4
Molecular Weight	338.67 g/mol
Synonyms	Tris(trimethylsilyl)(trifluoroacetyl)silane; (Trifluoroacetyl)tris(trimethylsilyl)silane; Silane, tris(trimethylsilyl)(trifluoroacetyl)-; Trifluoroacetyltris(trimethylsilyl)silane; (Trifluoroacetyl)silane tris(trimethylsilyl) derivative; TASF (in some contexts as a reagent variant); CF3C(O)Si(SiMe3)3
EINECS	Contact for details

Quality Control

Our Trifluoroacetyl-Tris(Trimethylsilyl)Silane is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture ingress and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.