Description

tert-Butyl Isonicotinate is a high-purity chemical intermediate featuring a tert-butyl ester group attached to the isonicotinic acid core. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly in the construction of complex pharmaceutical molecules and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the life sciences sector for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isonicotinate moiety can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions, crucial for modern organic chemistry.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its rigid pyridine structure.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, specialized ester derivatives.

Basic Information

Product Name	tert-Butyl Isonicotinate
CAS No.	81660-73-3
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	4-Pyridinecarboxylic acid, 1,1-dimethylethyl ester; Isonicotinic acid tert-butyl ester; tert-Butyl 4-pyridinecarboxylate; 1,1-Dimethylethyl isonicotinate; 4-(tert-Butoxycarbonyl)pyridine; t-Butyl isonicotinate
EINECS	Contact for details

Quality Control

Our tert-Butyl Isonicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.