Description

4-Hydroxyequilin is a key estrogenic steroid derivative and a significant metabolite of equilin, offering a high-purity reference standard for research and development. This compound is critical for analytical and pharmaceutical applications where precise chemical structure and purity are paramount. It is primarily utilized by research institutions, pharmaceutical developers, and quality control laboratories engaged in steroid hormone analysis, metabolic studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity certified reference material (CRM) for the calibration of analytical instruments and validation of testing methods in pharmaceutical quality control.
• Biochemical Research: Used as a critical reagent in metabolic pathway studies, enzyme interaction assays, and research into estrogen receptor activity and hormone-dependent processes.
• Analytical Chemistry: Employed as an internal standard or calibration compound in advanced chromatographic techniques such as HPLC and LC-MS for the quantification of estrogenic compounds in complex matrices.
• Drug Development: Acts as a key intermediate or a pharmacological probe in the synthesis and biological evaluation of new steroid-based therapeutics and hormone replacement therapies.
• Diagnostic Kit Manufacturing: Utilized in the production and quality assurance of diagnostic assays and kits designed to measure hormone levels in clinical and research settings.

Basic Information

Product Name	4-Hydroxyequilin
CAS No.	81608-62-0
Molecular Formula	C18H20O3
Molecular Weight	284.35 g/mol
Synonyms	4-Hydroxyequilin; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one; Equilin-4-ol; 1,3,5(10),7-Estratetraene-3,4,17-triol-17-one; 4,17β-Dihydroxyestra-1,3,5(10),7-tetraen-3-ol-17-one; 4-Hydroxy-17-oxoestra-1,3,5(10),7-tetraen-3-ol
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxyequilin is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results from spectroscopic, chromatographic, and other relevant analytical methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.