Description

3-Benzo[1,3]Dioxol-5-Yl-3-Oxo-Propionic Acid Ethyl Ester is a high-purity organic building block and key intermediate in advanced chemical synthesis. This compound matters for its role as a versatile precursor in the development of complex molecules, offering a reactive β-ketoester moiety adjacent to a benzodioxole ring system. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for constructing heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those containing benzodioxole or chromone-related scaffolds.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its reactive ketone and ester functionalities.
• Fine Chemical Building Block: Serves as a versatile starting material for synthesizing specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: Employed in organic chemistry research for studying cyclization reactions, Claisen condensations, and the development of new synthetic methodologies.
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	3-Benzo[1,3]Dioxol-5-Yl-3-Oxo-Propionic Acid Ethyl Ester
CAS No.	81581-27-3
Molecular Formula	C12H12O5
Molecular Weight	236.22 g/mol
Synonyms	Ethyl 3-(1,3-Benzodioxol-5-yl)-3-oxopropanoate; 3-(1,3-Benzodioxol-5-yl)-3-oxopropanoic acid ethyl ester; Ethyl 3-oxo-3-(benzo[d][1,3]dioxol-5-yl)propanoate; 3-Oxo-3-(1,3-benzodioxol-5-yl)propionic acid ethyl ester; 5-Acetyl-1,3-benzodioxole-5-carboxylic acid ethyl ester (tautomeric form); β-Keto ester intermediate; 3-(Benzo[1,3]dioxol-5-yl)-3-oxopropionic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Benzo[1,3]Dioxol-5-Yl-3-Oxo-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.