Description

2-Chloro-4,6-Bis(Trifluoromethyl)Pyridine is a high-value, multi-functional fluorinated pyridine building block essential for advanced chemical synthesis. Its unique structure, featuring chlorine and two trifluoromethyl groups, provides exceptional reactivity and lipophilicity, making it a critical intermediate for creating complex molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and catalysts used in cross-coupling and other metal-catalyzed reactions.
• Material Science Research: Employed in the creation of fluorinated polymers and advanced organic electronic materials to modify electronic properties and stability.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Chloro-4,6-Bis(Trifluoromethyl)Pyridine
CAS No.	81565-21-1
Molecular Formula	C7H2ClF6N
Molecular Weight	249.54 g/mol
Synonyms	2-Chloro-4,6-bis(trifluoromethyl)pyridine; 4,6-Bis(trifluoromethyl)-2-chloropyridine; 2-Chloro-4,6-di(trifluoromethyl)pyridine; Pyridine, 2-chloro-4,6-bis(trifluoromethyl)-; 2-Chloro-α,α,α,α',α',α'-hexafluoro-4,6-lutidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4,6-Bis(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.