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2,3,6-Trichloro-4-(Trifluoromethyl)Pyridine CAS NO 81565-20-0


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CAS No.:81565-20-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,3,6-Trichloro-4-(Trifluoromethyl)Pyridine is a high-purity halogenated pyridine derivative that serves as a critical advanced intermediate in modern chemical synthesis. Its unique structure, combining chlorine and fluorine substituents, makes it a versatile building block for creating complex molecules with tailored properties. This compound is essential for R&D and production chemists in the agrochemical and pharmaceutical industries, where it is used to develop novel active ingredients and functional materials.

Application

  • Agrochemical Intermediate: A key precursor in the synthesis of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
  • Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of active pharmaceutical ingredients (APIs), particularly those requiring halogenated heterocycles.
  • Material Science Research: Serves as a specialty monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and electronic materials.
  • Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to introduce the 2,3,6-trichloro-4-(trifluoromethyl)pyridyl group into target molecules.

Basic Information

Product Name 2,3,6-Trichloro-4-(trifluoromethyl)Pyridine
CAS No. 81565-20-0
Molecular Formula C6HCl3F3N
Molecular Weight 230.43 g/mol
Synonyms 2,3,6-Trichloro-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-2,3,6-trichloropyridine; 2,3,6-Trichloro-α,α,α-trifluoro-4-picoline; Pyridine, 2,3,6-trichloro-4-(trifluoromethyl)-; 2,3,6-Trichloro-4-trifluoromethylpyridine
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Quality Control

Every batch of 2,3,6-Trichloro-4-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system to ensure consistency and reliability for your synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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