Description

2-Chloro-4-(Trifluoromethyl)Pyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it a high-value intermediate for creating compounds with tailored properties. This product is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and functional polymers.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethyl)Pyridine
CAS No.	81565-18-6
Molecular Formula	C6H3ClF3N
Molecular Weight	181.54 g/mol
Synonyms	2-Chloro-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-2-chloropyridine; 2-Chloro-4-trifluoromethylpyridine; 2-Chloro-α,α,α-trifluoro-4-picoline; Pyridine, 2-chloro-4-(trifluoromethyl)-; 81565-18-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Trifluoromethyl)Pyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.