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Dihydroartemisinin CAS NO 81496-82-4


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CAS No.:81496-82-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dihydroartemisinin is a potent, semi-synthetic derivative of artemisinin and a key active pharmaceutical ingredient (API) in antimalarial therapies. Its primary value lies in its high efficacy against Plasmodium falciparum malaria, including strains resistant to chloroquine and other drugs. This compound is essential for manufacturers in the pharmaceutical industry producing combination therapies (ACTs) and for research institutions developing new antiparasitic formulations.

Application

  • Active Pharmaceutical Ingredient (API) in Artemisinin-based Combination Therapies (ACTs) for malaria treatment.
  • Pharmaceutical Intermediates for the synthesis of more complex artemisinin derivatives.
  • Biomedical Research for studying antimalarial mechanisms of action and drug resistance.
  • Reference Standard in analytical laboratories for quality control and method validation.
  • Veterinary Pharmaceuticals for the treatment of parasitic infections in animals.
  • Preclinical & Clinical Development of new antiparasitic and potential anticancer agents.

Basic Information

Product Name Dihydroartemisinin
CAS No. 81496-82-4
Molecular Formula C15H24O5
Molecular Weight 284.35 g/mol
Synonyms Artenimol; Dihydroqinghaosu; DHA; Arteannuin B; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; WR 256283
EINECS Contact for details

Quality Control

Our Dihydroartemisinin is manufactured under strict quality systems. It undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for pharmaceutical use. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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