Description

α-Dihydroartemisinin is a key pharmaceutical intermediate and active metabolite derived from artemisinin. This compound is critical for the development and production of next-generation antimalarial drugs, particularly artemisinin-based combination therapies (ACTs). It is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers focused on global health initiatives and advanced therapeutic synthesis.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Primary intermediate in the manufacture of potent artemisinin-derived antimalarial agents.
• Pharmaceutical Research & Development: Crucial reference standard and building block for developing new artemisinin analogs and combination therapies.
• Antimalarial Drug Production: Used in the commercial-scale synthesis of drugs like artemether, arteether, and artesunate.
• Biochemical Studies: Serves as a probe for investigating the mechanism of action of artemisinin against Plasmodium parasites.
• Veterinary Pharmaceutical Applications: Potential use in developing antiparasitic treatments for animals.

Basic Information

Item	Details
Product Name	α-Dihydroartemisinin
CAS No.	81496-81-3
Molecular Formula	C15H24O5
Molecular Weight	284.35 g/mol
Synonyms	Dihydroartemisinin; α-Dihydroartemisinin; DHA; Arteannuin B; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; Arthemeter Impurity A; Artemisinin, dihydro-
EINECS	Contact for details

Quality Control

Our α-Dihydroartemisinin is produced under strict quality management systems. Each batch is tested to ensure high purity and compliance with relevant pharmacopeial standards where applicable. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.