Description

tert-Butyl (2,2,2-Trifluoroacetyl)Carbamate is a specialized, high-purity chemical building block used in advanced organic synthesis. This compound is valued for its role as a protected intermediate, enabling the controlled introduction of functional groups in complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoroacetyl-protected amine functionalities.
• Peptide Synthesis: Used as a protecting group reagent for amines during solid-phase and solution-phase peptide synthesis, offering orthogonal deprotection strategies.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides with enhanced properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocycles and other advanced organic molecules.
• Material Science: Potential use as a monomer or modifier in the synthesis of specialty polymers and advanced materials.

Basic Information

Product Name	tert-Butyl (2,2,2-Trifluoroacetyl)Carbamate
CAS No.	81464-59-7
Molecular Formula	C7H10F3NO3
Molecular Weight	213.16 g/mol
Synonyms	Boc-Trifluoroacetamide; N-(tert-Butoxycarbonyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[(2-methyl-2-propanyloxy)carbonyl]acetamide; tert-Butyl N-(2,2,2-trifluoroacetyl)carbamate; (Boc)NHCOCF3; N-Boc-trifluoroacetamide; tert-Butoxycarbonyl trifluoroacetamide
EINECS	Contact for details

Quality Control

Our tert-Butyl (2,2,2-Trifluoroacetyl)Carbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.